Misery

"You're my number-one fan."

While Paul is unconscious after his accident, he hears a distorted version of Annie saying she's his 'number-one fan.' By the time he rouses, he's able to cut Annie off before she can introduce herself as such. 

"That was only one of the things about Annie that scared him." 

Within his first few days of consciousness, Paul discovers that Annie doesn't know exactly what she's doing in terms of his care. He also discovers that Annie has a huge amount of Novril, that he's hooked on the Novril, and that Annie is "dangerously crazy" (10). 

"She was crazy but he needed her." 

Like Stephen King needed his drugs of choice and fan base, Paul depends on Annie to live. She feeds Paul, tends to his injuries, and administers his pain medication. Though Annie is Paul's captor, he depends on her. This relationship dictates the course of the novel.