Sydney is a brilliant but cynical and depressed English lawyer who works alongside Mr. Stryver. He struggles with alcoholism and a deep sense of apathy, often referring to himself as a disappointed drudge. Despite his sharp legal mind, he lacks professional ambition and handles the grueling legwork for his partner's cases.

Charles is a handsome, courteous young Frenchman living in England as a tutor. He holds progressive views that put him at odds with the French aristocracy. He seeks to build an honest, hardworking life in London, distancing himself from the cruelty associated with the French upper classes.

Lucie is a gentle, compassionate young woman with distinctive blonde hair, raised in England after the death of her mother. She discovers that the father she thought was dead has been imprisoned in France for eighteen years. Her unwavering devotion and domestic warmth serve as a stabilizing force for the traumatized people around her.

Thérèse runs a wine-shop with her husband in an impoverished area of Paris. She is a watchful, composed woman who constantly knits, silently observing everything around her. Beneath her calm exterior lies a fierce, implacable anger toward the French aristocracy, driven by the intense suffering of her family.

Ernest is a resolute, determined wine-shop keeper in the Saint Antoine slum of Paris. He serves as a leader in a secret revolutionary society organizing against the French monarchy. Despite his commitment to the uprising, he retains a sense of loyalty and compassion toward his former master.

Doctor Manette is a once-successful French physician who was secretly imprisoned in the Bastille for eighteen years. The trauma of his confinement leaves him psychologically fragile, initially remembering nothing of his past life. He slowly regains his intellectual bearing and medical practice in London, though he remains vulnerable to periods of dissociative relapse.

Mr. Lorry is an elderly, methodical banker working for Tellson's Bank in London and Paris. He insists that he is merely a machine of business, lacking personal feelings or attachments. However, his actions reveal a deeply loyal and protective nature, especially regarding the clients he guides through moments of crisis.

Mr. Stryver is a stout, loud, and ambitious English lawyer striving for a lucrative practice. He lacks legal analytical skills but possesses a glib, confident courtroom presence. He frequently relies on others to do the actual work while taking all the credit and viewing himself as highly desirable.

Miss Pross is Lucie's formidable, red-haired English maid and fierce protector. She is loud, intensely loyal, and entirely suspicious of anyone who might threaten her mistress's happiness. Despite her brash exterior, she is driven by deep, selfless love for the people she considers family.

The Marquis is a haughty, cruel French nobleman with a face like a fine mask. He embodies the worst excesses of the Ancien Régime, treating the lower classes as little more than animals. He actively enjoys using fear and oppression to maintain his family's luxurious lifestyle and absolute power.

Jerry is a gruff, spiky-haired odd-job man who runs errands for Tellson's Bank by day. By night, he secretly works as a 'Resurrection-Man,' illegally digging up graves to sell bodies to medical students. He is suspicious of his wife's religious devotion, believing her prayers interfere with his illicit nocturnal business.

The Seamstress is a young, innocent peasant woman caught up in the indiscriminate executions of the new Republic. She is gentle, fearful, and confused by how her death could possibly benefit the revolution. She seeks comfort and human connection in her final moments.

John Barsad is a deceitful gambler and professional spy. He shifts his allegiances based on whoever pays him, working variously for the English government, the French monarchy, and the French Republic. He is an opportunistic survivor who carefully works his way through dangerous political situations to protect himself.

Monseigneur is a decadent, highly influential French nobleman. He symbolizes the greed, vanity, and sheer incompetence of the French aristocracy. He completely ignores the poverty ravaging France in favor of empty social rituals and self-enrichment.

This rural laborer initially repairs roads near the Evrémonde estate. He is gullible but observant, easily swept up in the spectacles of the aristocracy. Later, he moves to Paris, takes up wood-sawing near a prison, and falls completely under the influence of the revolutionary leaders.

Jacques Three is a bloodthirsty, predatory member of the revolutionary society in Saint Antoine. He represents the violent, cannibalistic hunger of the mob, eagerly anticipating the execution of aristocrats. He consistently supports the most ruthless actions of the revolution's leaders.

The Vengeance is the wife of a local grocer who becomes Thérèse Defarge's fiercely loyal lieutenant. She embodies the unchecked rage and vindictiveness of the oppressed French populace. She orchestrates mob violence with gleeful enthusiasm, fully embracing the new era of bloodshed.

Gaspard is a desperate, impoverished resident of Paris. Driven to madness by the tragic death of his young child beneath an aristocrat's carriage wheels, he takes drastic and fatal action. His actions serve as a catalyst for the building revolutionary fervor.

Gabelle is the tax collector and estate manager for the Evrémonde family in France. He attempts to follow orders to stop collecting oppressive taxes, but his long association with the aristocracy makes him a target of the angry peasantry. His desperate plea for help sets major events in motion.

Roger Cly is a deceptive, opportunistic spy and conman. He operates quietly to protect himself from public outrage in England. He relocates to France to continue his dangerous espionage work inside the shifting political environment.

Little Lucie is the young, observant daughter of Charles and Lucie. She inherits her mother's compassionate nature and brings joy to the extended family circle. She possesses a unique, childlike ability to see past the cynical exteriors of troubled adults.

Young Jerry is a boy who closely mirrors his father's gruff mannerisms and eagerly hopes to follow in his secret footsteps. Mrs. Cruncher is a devout, anxious woman who suffers physical abuse for constantly praying, driven by deep guilt over her husband's unsavory nightly activities.