Bernard is an Alpha Plus psychologist working at the Psychology Bureau in the Central London Hatchery. He is noticeably shorter than others in his high caste, which fuels a deep inferiority complex and feeds rumors that alcohol was accidentally added to his blood surrogate during gestation. He harbors resentment for the World State's enforced conformity and frequently refuses the state-mandated drug soma, but his rebellion is driven more by a desire for social acceptance than by true ideological independence.

Lenina is a vaccination worker at the Hatchery who generally adheres to the World State's conditioning, frequently reciting sleep-taught hypnopaedic slogans in everyday conversation. She is exceptionally attractive and popular, typically living a life of mandated promiscuity and eager consumerism. Despite her overall conformity, she exhibits a slight rebellious streak by occasionally dating the same man for unusually long periods and showing an unexpected attraction to the socially outcast Bernard Marx.

John is a young man raised on the Savage Reservation in Malpais, existing uncomfortably between two worlds. Born to a civilized mother but raised among the native population, he is shunned by his peers for his pale skin and his mother's unorthodox behavior. Educated primarily through an abandoned volume of Shakespeare's complete works, he views the world through an intense and highly moralistic lens that clashes violently with the sterile reality of the World State.

The Director of Hatcheries and Conditioning is an authoritative, fastidious figurehead of the World State's reproductive and social systems. He firmly upholds the societal values of community and stability, enforcing strict adherence to infantile decorum among his workers. Beneath his staunchly orthodox exterior, he harbors a deeply guarded secret about a past visit to the Savage Reservation.

Mustapha Mond is the Resident World Controller for Western Europe, one of only ten individuals who rule the globe. While he oversees the suppression of historical texts and art to maintain societal order, he secretly possesses access to forbidden literature like Shakespeare and the Bible. He is an exceptionally intelligent and pragmatic leader who fully understands the sacrifices required to sustain a pain-free civilization.

Linda is a former Beta worker from the Fertilizing Room who was lost and left behind at the Savage Reservation over twenty years ago. Stripped of the World State's comforts and conditioning, she copes with her isolation by consuming mescal as a substitute for soma. She finds it difficult to reconcile her conditioned beliefs in promiscuity and consumerism with the traditional, monogamous culture of the reservation, leading to her ostracization by the local women.

Henry is a high-level worker at the Hatchery and Conditioning Centre who embodies the ideal citizen of the World State. He is conventionally attractive, punctual, and fully adheres to societal norms, viewing life strictly through the lens of scientific efficiency and statistical output. He serves as a sharp contrast to the disgruntled and socially awkward Bernard Marx.

Helmholtz is an Alpha Plus lecturer and emotional engineer who writes state-sponsored propaganda. Exceptionally intelligent and widely admired, he nevertheless feels a profound sense of emptiness and dissatisfaction with his superficial work. He longs to use his writing to express something meaningful, making him a natural confidant for others who feel alienated by the World State.

Fanny is a worker at the Hatchery and a close confidante to Lenina. She is a model citizen who actively encourages Lenina to adhere to the World State's mandate of promiscuity and consumerism, frequently expressing dismay when her friend shows interest in monogamy or unconventional men.

Popé is a man living on the Savage Reservation who brings Linda mescal and acts as one of her romantic companions. He introduces a critical element into John's life by leaving behind a volume of Shakespeare's complete works, inadvertently giving the boy the vocabulary to express his intense hatred for Popé's presence.

Benito is a highly orthodox, good-natured citizen of the World State and a former dating companion of Lenina. He represents the well-adjusted, soma-taking majority, whose constant good cheer and lack of introspection deeply irritate the brooding Bernard Marx.