Vance’s maternal grandmother and a significant maternal figure to him, known for her strong influence on his values and educational aspirations.

Vance's biological mother who struggles with addiction and influences his upbringing with her inconsistent presence and behavior.

Vance’s half-sister who frequently takes on a caretaking role due to their mother’s challenges and remains a close confidante.

Vance’s maternal grandfather who works at Armco Steel, formerly a violent alcoholic, and plays a role in Vance’s early life.

Vance's wife, whom he meets at Yale Law School, supporting him through his uncertainties and helping him navigate their life together.

Lindsay’s husband, regarded positively by the family and distinguished by not being of Kentucky hillbilly origin.

The son of Lindsay and Kevin, who shares a positive bond with Vance and Mamaw.

Vance's aunt who overcomes early challenges to have a successful career and stable family life.

Aunt Wee's husband and a positive presence in Vance’s family, not from Kentucky hillbilly background.

Vance's great-grandmother who lives in Kentucky and is a reason for family reunions and trips.

Vance’s biological father who becomes a Pentecostal Christian, providing a stable and peaceful home environment during Vance’s adolescence.

Vance’s adoptive father and third husband to Bev, known for his kind demeanor despite a stereotypical hillbilly appearance.

Two of Bev’s brief romantic partners during Vance's childhood, each with distinct personal challenges.

Bev’s boyfriend during a brief period in Dayton, noted for his inability to manage Bev's tumultuous nature.

Bev's fifth husband and boss, who is part of a chaotic family dynamic involving Vance’s teenage years.

Mamaw’s siblings associated with Vance’s Kentucky heritage and hillbilly culture.