Greta is a 45-year-old woman who recently relocated to Hudson, New York, after a traumatic incident at her former pharmacy job. Seeking a fresh start, she works as an audio transcriber for a local sex and relationship therapist. This role allows her to remain isolated while listening to the intimate secrets of others. She is particularly captivated by the voice of a patient she dubs "Big Swiss," whose therapy sessions she meticulously types up.

Flavia, whom Greta privately nicknames "Big Swiss," is a 28-year-old gynecologist originally from Switzerland. She leads an affluent life in Hudson with her husband but attends sex therapy to address her inability to achieve an orgasm. Stoic and beautiful, she strictly compartmentalizes a severe past assault, refusing to let the attack define her present life or her identity.

Sabine is Greta's old friend and current landlord in Hudson. She is a generous woman who opens her home to various people, animals, and even an indoor beehive. Struggling with a recent loss of financial stability and substance abuse, Sabine uses her chaotic home environment as a distraction from her internal conflicts.

Keith is a man from a well-established Hudson family who spent eight years in prison for severely assaulting Flavia when she was twenty years old. His impending release from prison casts a shadow of anxiety over Flavia's life, generating fears that he might return to stalk her.

Om is an eccentric, new-age sex and relationship therapist practicing in the gossip-heavy town of Hudson. He dictates his patient sessions into audio recordings for a book he is writing, employing Greta to transcribe them. He frequently pushes his patients to confront the deeper emotional roots of their physical intimacy issues.

Stacy is Greta's former fiancé of ten years, a supportive man from Boston. He encouraged Greta to seek professional help after her workplace trauma, an intervention that ultimately led to her ending their relationship and moving across the country.

Luke is Flavia's husband of six years. He suggested his wife seek sex therapy and spends his free time watching other people play his favorite video games. He enjoys a comfortable lifestyle with his wife and hopes to start a family.

Nicole is a Hudson resident and one of Om's therapy patients. She struggles with relationship issues and past trauma, occasionally bringing up pop culture coping mechanisms during her recorded sessions.

Ryan is Nicole's partner and another of Om's individual therapy patients. He and Nicole work through their emotional hurdles while living in the interconnected local community.

Piñon is the dog Greta co-adopted with her ex-fiancé Stacy and took with her to Hudson. He represents a source of pure, uncomplicated affection for Greta, contrasting sharply with her messy human interactions.

Seymour is Sabine's father. He occasionally spends time at Sabine's dilapidated house and expresses a superficial attraction to Greta when she first moves in.

Mateo is Sabine's twenty-year-old adopted son. He occupies space in Sabine's crowded household and catches Greta's wandering eye early in her stay.

Hopper was the pharmacist and Greta's boss at her previous job. His tragic death following an armed robbery served as the catalyst for Greta's drastic life changes.

Gideon is a local beekeeper. Sabine calls him in to manage the massive bee swarm that breaks out in her kitchen.

Vera is a local bartender at a dive bar in Hudson and the sister of Keith. She represents the long-standing, interconnected local families in the gentrifying town.