The novel opens with an unnamed narrator standing outside a mansion at night, armed and addressing a dead girl, vowing to make the man inside scream her name. Interspersed throughout the book are excerpts from a UCLA PhD dissertation by Frances Vogel titled "Our Ladies of the Dark: A History," framing the narrative as the first official account of a group of female outlaws whose actions inspired a broader cultural movement.
In the present day, Detective Grey Holloway, a 27-year-old Los Angeles Police Department (LAPD) robbery-homicide detective, investigates the murder of Elizabeth Drake in a Bel Air mansion. Drake has been shot execution-style, and a lyric by pop singer Scout Sage is written in blood on the bedroom wall. Grey's father, once a respected detective, died after being disgraced by the LAPD, and her older sister Alice went missing years earlier. Grey joined the force to continue her father's work and maintains a 100 percent clearance rate despite being mocked as "Detective Barbie" for moonlighting as a bottle service girl at the Serpent Room nightclub.
Ten years earlier, Isabel Cruz, Scout's childhood best friend and fellow aspiring actress, narrates the night they attend Easton Banks's Christmas party in the Hollywood Hills. Both play cheerleaders on a teen TV show produced by Easton's network. Scout's younger sister Georgia, a freshman at the University of Southern California (USC), secured their invitation through Alden Banks, Easton's socially awkward son, who is infatuated with her. They arrive with Isabel's boyfriend, Brooks Yardley, hoping to network with Easton and his powerful associate Reese Griffin. At the party they also encounter Dakota Banks, Easton's teenage sister, and Emmy Nolan, Dakota's aspiring-actress best friend.
Around midnight, Georgia vanishes. Directed to the pool house, they find her body on a bed, bruises shaped like fingers covering her chest and neck, a wound gaping in her head. At the LAPD station, officer Carmen Ellis warns Scout and Isabel that the Banks family's attorneys will make prosecution difficult. At Georgia's funeral, the district attorney declines to file charges. Scout becomes cold and detached. She and Isabel break into the Banks mansion, handcuff Alden to his bed, and carve Georgia's name into his chest with a pocketknife. The next day, Alden is found dead by hanging, the carved name interpreted as a guilt-driven confession. Scout and Isabel are not suspected. Isabel says Alden killed himself because of what they did. Scout responds: "Good."
In the present, Ellis, now Grey's partner, discovers Drake was Reese Griffin's assistant, complicit in facilitating Griffin's assaults on young actresses. Ellis theorizes that a pattern of revenge killings targeting people who hurt women connects to Scout, who leaves coded lyrics at each crime scene. Grey commits to investigating, but the partnership collapses when Ellis is caught attempting to break into Scout's home with surveillance photos, rope, and bleach in her car trunk. Grey realizes Ellis was driven by obsession rather than evidence.
Meanwhile, Juliet Stone, an 18-year-old model, approaches Scout's entourage at the Serpent Room, desperate for help escaping an exploitative agent. Scout's circle takes Juliet in and confronts the agent, with Scout pulling a handgun when he turns violent. Grey, working undercover at the club as "Grey Hollis," notices Scout's excessive hair shedding and conceives a plan involving DNA evidence. When Scout is brought in for questioning, police reveal her hair was found in Drake's bathroom, matched against Georgia's DNA in the LAPD system. Scout and Isabel conclude someone is framing her.
In a parallel timeline, journalist Rosie Wright investigates a rumored "hot girl murder club" led by Scout, concludes Alden likely did not kill Georgia, and publishes her exposé in
The New York Times. Readers overwhelmingly celebrate Scout as a hero. Rosie obtains video journals in which Georgia alludes to a secret relationship most people would not approve of, but before she can pursue this lead, Rosie is found bludgeoned to death with another Scout lyric on her wall.
Isabel contacts Brooks, now a Federal Bureau of Investigation (FBI) agent, for help. Scout, Isabel, and Brooks visit Dakota Banks, who reveals Alden's alibi: He was in her bedroom from 11 p.m. onward, confirmed by witnesses who escorted him there after Georgia rejected him. Scout collapses at the realization that Alden was innocent. Through a retired network executive and a private investigator's files, they discover surveillance photos proving Georgia's secret boyfriend was Easton Banks. The investigator also has photos of Easton, Reese, and billionaire tech mogul Gabriel Knox with two Serpent Room employees who vanished the following day. A chapter set 12 years earlier reveals one of these women to be Alice Holloway, Grey's sister, who left with the men for an after-party at Gabriel's desert house.
Scout confronts Easton at his Malibu mansion. He admits he choked Georgia during sex until she lost consciousness but insists he did not kill her. After a struggle, Emmy Banks, née Nolan, appears with a gun. A flashback reveals Emmy hiding in the pool house closet that night, watching Easton choke Georgia unconscious. When he panicked, Emmy offered to handle the situation; with his silent nod, she struck Georgia with a decorative lamp, killing her, then used the murder as leverage to marry Easton. In the present, Emmy reveals her role in Georgia's death, then shoots Easton dead. Brooks, whom Scout secretly called, bursts in and arrests Emmy. Emmy reveals she was working with an unnamed partner who wanted Easton dead.
That same day, Juliet plants a bomb at the Knox Aeronautics tower during a rally organized by Luca Clearwater, a Harvard Law-educated activist whose Green Lions organization opposes Gabriel Knox's presidential campaign. The explosion is far more powerful than Luca promised. Grey arrests Juliet after receiving an anonymous tip, and security footage Luca promised would be disabled captures Juliet on camera.
Scout sacrifices herself, confessing to the bombing with fabricated evidence in exchange for Juliet's release. She offers Grey surveillance photos showing Alice at the Serpent Room with Easton, Reese, and Gabriel. Grey recognizes her sister but cannot free Juliet. Scout's lawyer produces a signed confession, and Isabel weeps as Scout formally takes the blame.
Grey arrests Luca, who reveals her true identity: She is Daisy Chapman, the other missing Serpent Room employee. She and Alice were taken to Gabriel's desert house, where the men attacked them. Gabriel beat Daisy so severely she required extensive facial reconstruction. The men buried both women in sand, believing them dead. Daisy clawed her way out, reinvented herself, and spent years plotting to destroy Knox. She befriended Drake, who drunkenly revealed Knox owned a desert house but refused to cooperate with police when sober. Grey arrests Daisy for the murders of Drake, documentary filmmaker Simon Markham, and Wright. Markham had helped whitewash Knox's image through a documentary. Grey privately promises to find Alice.
Isabel burns Scout's diaries as instructed but resolves to preserve the legacy of their work. Brooks arrives, and the two reconcile after years apart. At Scout's court appearance, Scout enters veiled in black, but Isabel pauses in the doorway and makes the sign of the cross, the secret gesture of Our Ladies of the Dark. The crowd erupts. Frances Vogel witnesses the moment and understands the movement continues.
The epilogue reveals the narrator from the prologue is Grey, addressing Alice. Knox was tried for the attacks on Alice and Daisy but acquitted because Alice's body was never recovered. Scout received a two-year sentence for arson from a sympathetic jury, and a woman ran for president backed by the Our Ladies of the Dark movement. Grey enters Knox's desert house with her service weapon, resolved to force him to reveal where Alice is buried, recover her remains, and bury Knox in her sister's place.