The deuteragonist facing terminal illness, driven by a desire to control her end-of-life experience, which creates a central conflict with her family.

Claire’s oldest friend, characterized by her loyalty and directness, who supports Claire’s controversial end-of-life choices.

Claire’s college roommate, known for her discipline and career focus, who joins Holly in caring for Claire.

Eliot and Claire’s daughter, a pediatrician concerned with family unity and her father’s dignity amidst the unfolding events.

Eliot and Claire’s son, an artistic and sensitive musician, who reacts passionately to the family’s tensions.

Holly’s ex-husband and a television writer, who provides an outsider’s perspective on the relationships and central conflict.

A memory of Claire’s, whose death becomes an idealized model for Claire’s end-of-life aspirations.