A predominantly Black neighborhood in San Francisco where Burke Harris works to improve health outcomes, illustrating both community resilience and challenges. The area is characterized by limited resources, affecting the health and well-being of its residents.

A wealthy, white technology entrepreneur who is a survivor of verbal and emotional abuse. Her story highlights the universal impact of ACEs, regardless of socioeconomic status.

A young mother and her toddler daughter dealing with failure to thrive due to emotional discord. Their story demonstrates the effectiveness of ACE-informed interventions in improving family health dynamics.

A patient of Burke Harris, introduced as a young boy whose growth was stunted following trauma. His ongoing journey signifies the complex challenges of managing stress responses linked to ACEs.

Evan is Nadine Burke Harris's brother whose life is impacted by ACEs, serving as a personal connection to the subject matter. Louis is the Burke sibling whose disappearance underscores the serious consequences of untreated childhood adversity.

The lead author of the seminal study connecting childhood abuse with adult health issues, inspiring Burke Harris's focus on ACEs. His work exemplifies the pioneering spirit in medical research, despite initial neglect.

A historical figure in epidemiology who pinpointed the source of a cholera outbreak by challenging prevailing theories. His approach influences Burke Harris's public health methodology and her pursuit of understanding health disparities.