Carter is a teenage magician and descendant of Egyptian pharaohs who carries heavy leadership responsibilities. He possesses a magical link to the war god Horus and serves as an unofficial leader for the Brooklyn House magicians. Carter questions his own abilities as a leader while trying to protect his peers from the chaos serpent Apophis.

Sadie is an impulsive, powerful teenage magician who was raised in London, separate from her brother Carter. She channels the magic of Isis, the goddess of magic, which often clashes with her own rebellious and hot-headed nature. Sadie protects her friends and refuses to abandon allies, such as when she seeks a cure for Bes's condition.

Walt Stone is a talented young magician and descendant of King Tutankhamun who suffers from a terminal blood curse. Anubis is the immortal Egyptian god of death, bound by ancient rules regarding his interactions with mortals. Both share a developing, complicated connection to Sadie Kane.

Zia Rashid is a highly trained Egyptian magician defending the Cairo stronghold against rebel forces. Ra is the ancient, aging sun god of Egyptian mythology whom Zia cares for. The two share a unique connection as Zia experiences blackouts and utilizes bursts of fire magic while tending to the senile deity.

Setne, originally known as Khaemwaset, is the deceased son of Ramses the Great and a morally ambiguous magician. He presents himself as a slick, manipulative figure who constantly seeks ways to evade underworld judgment for his past crimes. He possesses ancient knowledge necessary for defeating the forces of chaos.

Apophis is the ancient Egyptian serpent of chaos who aims to destroy the world and swallow the sun. He uses fear and false promises to create division among the magicians. He seeks to eradicate any magical texts that might contain the secret to his defeat.

Amos is Carter and Sadie's uncle and the leader of the Egyptian stronghold in Cairo. He acts as the defacto head of the magicians, though his controversial choice to accept the power of the gods has sparked a rebellion among his followers. He is a steadfast protector of his family and the world's magical order.

Julius is the father of Carter and Sadie, a former mortal magician who merged with the god Osiris. He now rules the Egyptian underworld as the god of judgment, weighing the souls of the dead. Though bound to his domain, he offers guidance and support to his children when they visit his realm.

Ruby is the deceased mother of Carter and Sadie, now existing as a spirit in the Egyptian underworld alongside her husband. She possesses deep magical knowledge and offers crucial emotional support and maternal advice to Sadie during times of extreme stress.

Bast is the Egyptian cat goddess who serves as the protector of the Brooklyn House stronghold. She spent millennia locked in combat with Apophis and understands the severe threat the chaos serpent poses. She provides tactical insight and acts as a magical guardian for the Kane family.

Bes is the Egyptian dwarf god who previously sacrificed his shadow to save Sadie's life. He currently exists in an unresponsive, vegetative state in a magical nursing home. Sadie refuses to abandon him and actively seeks a way to restore his lost spirit.

Thoth is the Egyptian god of wisdom and knowledge. He possesses the information needed to defeat Apophis but refuses to share it directly out of self-preservation, fearing the same magic could be used against him. He fights demons using highly unconventional, scholarly spells.

Horus is the Egyptian war god and the rightful pharaoh of the gods. He shares a psychic link with Carter, frequently urging the teenager to fully embrace his power and take over the world. He represents both incredible strength and a constant test of Carter's self-control.

Isis is the Egyptian goddess of magic and sorcery. She resides within Sadie Kane's mind, providing the teenager with immense magical abilities. Like Horus, Isis seeks to expand her own power and influence in the mortal world, forcing Sadie to carefully manage their connection.

Set is the Egyptian god of chaos, evil, and the desert. Despite his chaotic nature, he opposes Apophis's plan for total annihilation, preferring to maintain existence so he has a world to conquer. He is currently hosted by Amos Kane, though Carter remains highly suspicious of his motives.

Neith is the fierce Egyptian goddess of hunting. She guards the ancient ruins of Sais where Bes's shadow is located. She operates on strict deals and challenges, forcing Sadie and Walt into a deadly game of hide-and-seek before she will offer her assistance.

Leonid is a young Russian magician who travels to the Brooklyn House to deliver crucial intelligence. He channels the power of Shu, the god of the wind, which allows him to transport himself and Sadie safely to the Cairo stronghold.

Bloodstained Blade is a menacing demon with a double-bladed axe for a head. He serves as the captain of the Egyptian Queen and is magically bound to obey the Kane family, though Sadie correctly suspects he resents this servitude and may betray them.

Tawaret is the Egyptian hippopotamus goddess of motherhood and childbirth. She serves as a compassionate, dedicated nurse for elderly and forgotten gods, including Bes, expressing deep sorrow over their fading existence.

Face of Horror is an incredibly strong demon who serves as a physical mouthpiece for Apophis. Possessed by the chaos serpent, he physically overpowers Carter's magical defenses and whispers manipulative promises on behalf of his master.

Khufu is a magical baboon who resides at the Brooklyn House. He acts as a loyal companion, assistant, and messenger for the Kane family, participating in dangerous missions and helping to safeguard magical artifacts.

Hapi is a ridiculously cheerful, giant river god. Summoned using a spell provided by Setne, he effortlessly swats away river monsters and provides Carter and Zia with magical pills for rapid transport, while gleefully announcing they are heading into a trap.

Shu is the ancient Egyptian god of the wind and the great-grandfather of Anubis. He strictly enforces the rules regarding interaction between gods and mortals, intervening forcefully when Anubis breaks these protocols with Sadie.

Ammit is a fearsome underworld creature composed of lion, hippopotamus, and crocodile parts. Despite her terrifying purpose of eating the hearts of the wicked, she exhibits the playful, affectionate personality of an overly enthusiastic puppy toward Sadie.

Alyssa is a young, trainee magician residing at the Brooklyn House. She participates in missions alongside the senior magicians and attends a regular mortal school during the week, balancing her magical education with everyday teenage life.

Felix is a young trainee magician under the protection of the Brooklyn House. Like Alyssa, he assists the older magicians in securing artifacts and balancing his supernatural duties with a normal school schedule.