Meg's mother, who comes from a wealthy family and struggles with depression and anxiety, often self-medicating with alcohol, influencing her parenting and family dynamics.

Meg's father, known for his giddy and angry moods due to undiagnosed bipolar disorder and alcohol use, who later joins AA and tries to stabilize his life.

The eldest child in the Kissinger family, known for her artistic nature and rebelliousness, who later reveals her struggles with mental health during her college years.

Meg's intelligent and witty older sister, whose mental illness leads to volatility and several suicide attempts, impacting the family deeply.

Close in age to Meg, described as adventurous and supportive, who later pursues a career in medicine and advocates for mental health destigmatization.

The eldest boy in the family, who struggles with depression and the trauma of discovering his brother's body, whom Meg helps find supportive housing.

The third youngest child in the family, known for his mischievousness and athleticism, who finds solace in music as an adult.

The youngest boy, who battles feelings of inadequacy and makes poor decisions, ultimately diagnosed with bipolar disorder before his death by suicide.

The youngest daughter, who carries guilt from a family tragedy in her youth but later finds peace in nature.

Meg's paternal grandmother, an influential figure in the family known for her strong Irish Catholic faith and belief in the virtue of suffering.