David Charleston is a resourceful, non-Epic human who serves as the point man for the Newcago Reckoners. Driven by the past murder of his father, he dedicates his life to researching Epics and documenting their specific weaknesses. Despite his social awkwardness and habit of using terrible metaphors, he maintains a stubborn optimism, hoping to prove that Epics can overcome the corruption of their powers.

Jonathan Phaedrus, universally known as Prof, is the founder and leader of the Reckoners. He is secretly a High Epic who utilizes a technological loophole to avoid the corruptive influence of his powers by loaning them to his human team members. Prof is hardened, pragmatic, and heavily burdened by his past, staunchly believing that Epics are fundamentally dangerous and must be destroyed.

Regalia is the Epic ruler of Babilar (formerly New York City) who holds power over water. A former lawyer and preacher, she has flooded the metropolis, leaving only the upper floors of skyscrapers habitable. Unlike tyrannical Epics of the past, she provides a surprisingly relaxed, peaceful environment for her citizens, making her an unconventional dictator.

Megan, also known as the Epic Firefight, is a former Reckoner spy who previously infiltrated the Newcago team. She possesses powers tied to reality-bending and reincarnation. Now operating in Babilar, Megan struggles intensely against the corruptive influence of her Epic abilities, fighting to maintain her humanity while performing missions for Regalia.

Tia is a core member of the Newcago Reckoners who specializes in research, logistics, and intelligence gathering. She accompanies Prof and David to Babilar to help establish an operational foothold and decode Regalia's motives. Operating from a customized underwater submarine base, Tia acts as the grounded, analytical voice of the team.

Mizzy is the youngest and least experienced member of the Babilar Reckoner cell. She is eager to prove herself in combat and looks up to David for his success against High Epics. Her desperation to contribute often leads to friction during tactical planning, but she brings raw energy and dedication to the deeply entrenched team.

Exel is a former CIA spy who acts as the primary intelligence gatherer and community liaison for the Babilar Reckoners. He spends his time monitoring radio traffic and observing the remarkably peaceful citizens of the flooded city. Exel sometimes longs for the carefree life that Babilar's residents enjoy, questioning the absolute necessity of the Reckoners' endless war.

Val is a tough, experienced field operative for the Babilar Reckoners. She is known for her perpetual scowl and serious approach to their highly dangerous work. Having successfully eliminated an Epic in the past using quick, brutal thinking, she provides the team with pragmatic, hard-hitting combat support.

Obliteration is a highly dangerous, heat-absorbing Epic known for leveling entire cities after gathering sufficient energy. He views his destructive actions through a zealous religious lens, seeing himself as a doomsday omen. With an automatic teleportation ability that instantly removes him from physical danger, he presents a nearly impossible tactical challenge for the Reckoners.

Newton is a formidable Epic serving under Regalia who possesses the power to reverse kinetic force, effortlessly deflecting any physical attack back upon the attacker. She carries out Regalia's darker orders—such as destroying buildings—while also demonstrating an unusual desire to mingle with ordinary humans in Babilar's thriving social scene.

Sourcefield is an Epic who manipulates electricity and uses the steel structures of Newcago to transport herself rapidly across the city. She arrives seeking to claim Newcago after Steelheart's death but is swiftly countered by the Reckoners, who exploit her bizarre and highly specific weakness to a powdered drink mix.

Dawnslight is an enigmatic Epic operating in Babilar who is responsible for the strange, luminescent fruit and vines growing throughout the flooded skyscrapers. Unlike most Epics, Dawnslight's powers appear to create beauty and provide sustenance rather than causing destruction, making him a subject of near-worship among the local population.