Ash is a mother of two daughters who currently finds herself at a painful crossroads. She spends most of her days sitting with her terminally ill best friend, Edi, at a hospice care center in Massachusetts. Though technically married, she is separated from her husband Honey due to her own past infidelity, and she struggles to find emotional grounding as she faces the impending loss of her closest companion.

Edi is Ash's lifelong best friend who suffers from terminal ovarian cancer. Leaving her husband and young son behind in Brooklyn, she chooses to move into a hospice center near Ash so they can spend her final weeks together. She is practical, grounded, and often provides blunt but loving advice to Ash regarding her chaotic personal decisions.

Belle is Ash and Honey's teenage daughter, currently a self-sufficient junior in high school. She lives at home with Ash and acutely feels the strain of her parents' separation. Uniquely perceptive, she regularly speaks her mind openly and calls her mother out on her selfish behaviors.

Honey is Ash's estranged husband and the father of Jules and Belle. A former chef and private caterer who now owns a medical marijuana shop, he provides a stable and emotionally healthy presence for his family. Despite Ash's infidelity causing their separation, he remains closely involved in their lives and frequently brings them food.

Jules is Ash and Honey's older daughter. She currently attends college but remains connected to her family, occasionally returning home to provide support as Edi's health declines.

Jonah is Edi's brother who frequently visits the hospice center to spend time with his dying sister. He manages his own complicated grief while maintaining a casual, intimate physical relationship with Ash.

Jude is Edi's husband. He temporarily stays behind in New York to care for their young son while Edi resides in the Massachusetts hospice center, struggling with the intense emotional toll of his wife's illness.

Dash is Edi and Jude's young son. Edi conceived him after years of fertility treatments, and he remains in Brooklyn with his father while his mother receives end-of-life care.

Nicknamed "Dr. Soprano" by Ash and Edi, he is the oncologist treating Edi at the Graceful Shepherd hospice. He focuses on managing her pain medications while engaging in a secret physical relationship with Ash.

Cedar is the resident music therapist at the Graceful Shepherd hospice. He regularly plays songs for the patients and expresses absolute contentment with his quiet, non-famous life.

Myron is Edi and Jonah's father. He maintains a somewhat distant relationship with his children, communicating stiffly through text messages rather than visiting the hospice frequently.

Alice is a close childhood friend of Edi who visits the hospice center to offer support and share fond memories as Edi's condition rapidly worsens.

Gemma is an acquaintance of Ash whom Honey begins casually dating during his separation from Ash, an arrangement that causes Ash unexpected feelings of jealousy.

Scriv is Belle's "theyfriend" who frequently spends time with her family, including joining them for snowy outdoor activities at their home.

The resident chaplain at Shapely who helps families process the painful realities of terminal illness. He provides crucial advice to Ash regarding her role in Edi's final days, encouraging her to focus simply on being present.

Violet is a caring aid at the hospice center who helps manage the daily physical comforts and routines of the residents.

Ruth is another resident at the hospice center whose loud television provides a constant, theatrical soundtrack to Edi and Ash's days at the facility.