Discuss the representation of motherhood in the play. How do Agnes’s biological mother and Mother Miriam contrast in their influence on her?

Discuss the ethical implications of Dr. Livingstone’s methods. At what point does the play suggest that her pursuit of truth becomes harmful, if at all?

Consider the choice to structure the play around Dr. Livingstone’s monologues? Why does the play prioritize the voice of the skeptic (rather than, for example, Mother Miriam)?

Discuss the use of ambiguity in the play’s conclusion. Why does Pielmeier resist providing definitive answers?

Analyze the symbolism of blood in the play. How does it function in relation to guilt, sacrifice, and physical reality? Consider its Christian symbolism as well as its relationship to menstruation, childbirth, and (sexual) violence.

The play’s title puns on the similarity between the name “Agnes” and the phrase “Agnus Dei,” or “lamb of God,” an epithet for Jesus Christ. To what extent can Agnes be considered a Christ figure?

Analyze Agnes’s language and speech patterns. How do they reflect her psychological state and spiritual worldview?

Consider the words of the songs that Agnes sings, both secular and religious. How do they support the play’s overall meaning?